Clinical evidence
made clear.

Digestible analyses of clinical studies within longevity research, critically assessed and shaped into insights you can implement.

What Is Mitophagy? How It Supports Mitochondria, Energy and Healthy Ageing
22.07.2026

What Supplements Does David Sinclair Take? NMN, Resveratrol, Berberine and Spermidine Explained
If you are searching for what supplements David Sinclair takes, the clearest recent public answer includes: NMN, Resveratrol, Berberine, and Spermidine. In a recent interview, Sinclair separated more experimental compounds from the supplements he confidently recommends to the public, then...

READ MORE

What Supplements Does David Sinclair Take? NMN, Resveratrol, Berberine and Spermidine Explained

19.04.2026

Hallmarks of Ageing: The 12 Processes That Help Explain Why We Age
If you spend any time reading about longevity, one phrase comes up again and again: the hallmarks of ageing. That is because they offer one of the clearest frameworks for understanding what ageing actually is at a biological level. Instead...

READ MORE

Hallmarks of Ageing: The 12 Processes That Help Explain Why We Age

08.04.2026

David Sinclair on Diary of a CEO: Four Key Supplements Highlighted – NMN, Resveratrol, Berberine and Spermidine
Dr David Sinclair’s recent appearance on Diary of a CEO has put longevity supplements back into mainstream conversation. Dr Sinclair is a Harvard professor who has been studying aging, longevity and age reversal for 30 years.

READ MORE

David Sinclair on Diary of a CEO: Four Key Supplements Highlighted – NMN, Resveratrol, Berberine and Spermidine

30.03.2026

Cold Water Therapy Benefits: Ice Baths, Metabolism and Longevity
Cold water therapy, also known as cold water immersion or ice bathing, has become increasingly popular in recent years. From athletes and biohackers to wellness communities and endurance swimmers, cold exposure is often discussed as a tool for recovery, metabolism,...

READ MORE

Cold Water Therapy Benefits: Ice Baths, Metabolism and Longevity

24.03.2026

Sauna Benefits: What the Science Says About Heat Therapy and Longevity
Saunas have been used for centuries for relaxation and recovery, particularly in Nordic cultures. In recent years, however, sauna bathing has attracted growing attention in the scientific community because of its potential links to cardiovascular health, metabolic resilience, and longevity.

READ MORE

Sauna Benefits: What the Science Says About Heat Therapy and Longevity

17.03.2026

When Does Autophagy Start? The Science of Fasting and Cellular Renewal
If you search “when does autophagy start during fasting,” you will often find simple answers such as 12 hours, 16 hours, or 24 hours. These timelines are widely shared in health and biohacking communities, but the scientific reality is more...

READ MORE

When Does Autophagy Start? The Science of Fasting and Cellular Renewal

13.03.2026

GHK-Cu, CJC-1295 & More: Are These Peptides Safe?
In clinical medicine, certain peptides are FDA-approved and well studied. However, many trending compounds circulating online fall into a different category: “research chemicals” not approved for human use. That distinction matters.

READ MORE

GHK-Cu, CJC-1295 & More: Are These Peptides Safe?

09.03.2026

berberine patches
Berberine has become one of the most talked-about metabolic supplements - often framed online as a “natural Ozempic” alternative. As interest has surged, a newer format has followed: berberine patches marketed as a convenient, appetite-support option that “bypasses the gut.”

READ MORE

Berberine Patches vs Supplements: Do Berberine Patches Work (& Which Is Best)?

25.02.2026

Why Bryan Johnson Added Hyaluronic Acid to His Blueprint Stack
This week, Bryan Johnson publicly shared his updated skin-focused supplement protocol as part of the broader Bryan Johnson Blueprint, outlining how he approaches visible ageing and tissue preservation. Among the compounds he highlighted, one stood out for its simplicity: Hyaluronic Acid.

READ MORE

Why Bryan Johnson Added Hyaluronic Acid to His Blueprint Stack

24.02.2026

What Is Biological Age - and Why It Matters More Than Chronological Age
Most people measure ageing by the number of birthdays they’ve had. But modern longevity science increasingly shows that chronological age - the number of years you’ve been alive - tells only part of the story. What matters more is biological...

READ MORE

What Is Biological Age - and Why It Matters More Than Chronological Age

20.02.2026

@manapura.co